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The drug name is Contrave. Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you ought to err to the side of caution and let the FDA do its job and demand some study be done so the public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on their own medications. Researchers found out that participants using this drug for a year, lost weight within four weeks and have kept the weight off through the 56 weeks of the study. Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more effective and safer. Combo-pilling could be the newest fad or better yet the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription weightloss pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise blood pressure levels and pulse rate, and mustn't be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heart rate and must stop used in patients with uncontrolled high blood pressure levels, in addition to by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. Suboxone consists of two drugs; buprenorphine and naloxone. The naloxone is irrelevant in the event the addict uses the medication properly, but in the event the tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed in the liver shortly after uptake from your intestines and possesses no therapeutic effect. Buprenorphine may be the active substance; it can be absorbed within the tongue (and through the mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation in the event the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have also treated addicts who may have had gastric bypass, in which the first area of the intestine is bypassed along with the stomach contents empty right into a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy where the drug is taken up with the duodenum and transferred right to the liver from the portal vein, where it can be quickly and completely destroyed. After gastric bypass naloxone can be used up by areas of the intestine which aren't served through the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.