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Using two separate drugs to lose weight naturally can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err on the side of caution and let the FDA do its job and demand some investigation be done in order that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say everything to keep people on their medications. Researchers discovered that participants taking this drug to get a year, lost excess weight within one month and have kept the extra weight off through the entire 56 weeks with the study. Contrave is a combination from the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which might make them far better and safer. Combo-pilling could be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular may be the fact that as of right now there are no long term prescription weightloss pills that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise hypertension and heart rate, and mustn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high hypertension, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. Approving a drug using this type of many potentially lethal unwanted effects is inconsistent with all the mission statement of the FDA. The power with the drug manufacturing lobby is blatantly evident inside the approval of numerous drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety inside the US.